It is impossible to mute anyone from their profile (other methods take a very long time or require the griefer to be in your sight) until their profile information is loaded. This is a serious problem as recently there has been alot of work being done in this area on the LL servers which is causing us to not recieve profile information; but even when it should be back up, there is still often lag in this that lasts several minutes. For as long as we cannot mute them, griefers are free to spam us to death with particles and messages covering our screens.
Muting is done client side so it should not be a problem to have the "Mute" button always useable even before the profile is loaded.